Surprise! Most ‘color vision’ cells see only black or white | Science News for Students

Surprise! Most ‘color vision’ cells see only black or white

Many cells thought to sense color in fact read only whether something is white or not
Oct 19, 2016 — 7:00 am EST

Color vision may work a bit like filling in colors in a black-and-white coloring book, new research finds.

shironosov / istockphoto

The way people see color may be a bit like coloring in a black-and-white coloring book, a new study finds. The discovery means color vision may work very differently than scientists had thought.

The eyes see using many different types of cells. Each kind collects different information. Scientists have known for decades that some cells — known as cones —  detect color. They are part of the retina inside the back of the eye.

Cone cells can sense red, green or blue light. But Ramkumar Sabesan discovered that some of them sense white light — and only white light. That was a big surprise.

colored and uncolored dinosaurs
Many of the cells in your eye pnly detect black-and-white edges, like the outlines of these dinosaurs.
shironosov / istockphoto

Sabesan is a vision researcher at the University of Washington in Seattle. He and his colleagues at the University of California, Berkeley reported their unexpected finding September 14 in the journal Science Advances.

The team used a powerful microscope in their lab to peer into the eyes of two men. They created a map of about 1,000 cone cells in the retina. This map showed where the red, green and blue cones are. Then the scientists shone tiny spots of laser light onto individual red or green cone cells and asked the men what color they saw.

The so-called red and green cone cells each come in two types, they learned. One type transmitted white light. The other type relayed color. Especially surprising, far more cones reported seeing white light than either red or green. Out of 167 red cones tested, 119 signaled white; just 48 saw red. Out of 98 green cones tested, 77 reported white light and a mere 21 signaled green. There are very few blue cones in the retina. The researchers didn’t test those.

It is surprising that so few cones seem to detect color, even though all of them are able to, says Donald MacLeod. “It’s a rather inefficient arrangement,” says this vision researcher at the University of California, San Diego.

The large number of cells that detect white (and black, which is the absence of white) create a sharp black-and-white picture of someone’s surroundings. They provide crisp edges of visual details. The red- and green-signaling cells fill in the lines with blurrier chunks of color. The process works much like filling in a coloring book or adding color to a black-and-white film, says Sabesan.

The research is impressively difficult, notes Jay Neitz. He also is a vision scientist at the University of Washington in Seattle, but did not work with this team. He compares what they did to getting the first people to the moon. “It is a super technological achievement,” he says — “an amazing thing.

How they did it

To get a clear map of the retina, the researchers borrowed techniques that astronomers use to map things in space. Because the eye is constantly jiggling, the researchers also had to study patterns of the men’s eye movements. Only that way could they predict exactly where each cone cell would be a split second later when they targeted it with the laser beam.

In all, they stimulated 273 individual cone cells, one by one, in the volunteers’ eyes. The process took them about two years.

lasers on retinas
Researchers have learned surprising lessons about color vision by using precisely-targeted lasers (green line) to stimulate single cone cells (red, green and blue dots in inset) in human retinas (gray background).
R. Sabesan, Brian Schmidt, William Tuten, Austin Roorda

The findings suggest that the retina is doing more than scientists had thought. Cone cells were thought to read only red, green or blue colors. Scientists thought the brain did the hard work of combining those signals into a full-color view of the world (including black and white).

But instead, “the retina is doing more of the work,” says Neitz. The retina sends both black and white and color data to the brain. This makes the brain’s job easier. The researchers are now trying to understand how cone cells know whether to signal a color or the presence of white. How the different cell types are organized in the retina seems to be important in that decision. For example, red cones were more likely to signal white when they had been surrounded by green cones.

These findings could be good news for people with color blindness. If the right cones can be added to the retina, Neitz says, the human brain should easily be able to fill in one more color to its black-and-white picture.

Power Words

(for more about Power Words, click here)

cell     The smallest structural and functional unit of an organism. Typically too small to see with the naked eye, it consists of watery fluid surrounded by a membrane or wall. Animals are made of anywhere from thousands to trillions of cells, depending on their size. Some organisms, such as yeasts, molds, bacteria and some algae, are composed of only one cell.

colleague     Someone who works with another; a co-worker or team member.

data     Facts and/or statistics collected together for analysis but not necessarily organized in a way that give them meaning. For digital information (the type stored by computers), those data typically are numbers stored in a binary code, portrayed as strings of zeros and ones.

information     (as opposed to data) Facts provided or trends learned about something or someone, often as a result of studying data.

journal     (in science) A publication in which scientists share their research findings with the public. Some journals publish papers from all fields of science, technology, engineering and math, while others are specific to a single subject. The best journals are peer-reviewed: They send out all submitted articles to outside experts to be read and critiqued. The goal, here, is to prevent the publication of mistakes, fraud or sloppy work.

laser     A device that generates an intense beam of coherent light of a single color. Lasers are used in drilling and cutting, alignment and guidance, in data storage and in surgery.

microscope     An instrument used to view objects, like bacteria, or the single cells of plants or animals, that are too small to be visible to the unaided eye.

retina     A layer at the back of the eyeball containing cells that are sensitive to light and that trigger nerve impulses that travel along the optic nerve to the brain, where a visual image is formed.


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Journal:​ ​​ R. Sabesan et al. The elementary representation of spatial and color vision in the human retina. Science Advances. September 14, 2016, p. e1600797. doi: 10.1126/sciadv.1600797.